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Corresponding author*, Co-first author'

Select Publications

  • Lang H, Liu Y, Duan H, Zhang W, Hu X, Zheng H*

Identification of peptides from honeybee gut symbionts as potential antimicrobial agents against Melissococcus plutonius 

2023 Nat Commun 14:7650 DOI

 

  • Lang H, Wang H, Wang HQ, Zhong Z, Xie X, Zhang W, Guo J, Meng L, Hu X, Zhang X, Zheng H*

Engineered symbiotic bacteria interfering Nosema redox system inhibit microsporidia parasitism in honeybees

2023 Nat Commun 14:2778 DOI 

 

  • Zhang Z, Mu X, Cao Q, Shi Y, Hu X, Zheng H*

Honeybee gut Lactobacillus modulates host learning and memory behaviors via regulating tryptophan metabolism

2022 Nat Commun 13:2037 DOI

  • Zheng H*, Perreau JJ. Powell EJ, Han B, Zhang Z, Kwong WK, Tringe SG, Moran NA*

Division of labor in honey bee gut microbiota for plant polysaccharide digestion

2019 PNAS 116:25909–25916 DOI

Highlighted in Nat Rev Microbiol: Microbiome

Blog on JGI: Honey Bee Gut Microbiota Divvy Up Dinner

Referenced in Wikipedia

 

  • Zheng H*, Powell JE, Steele MI, Dietrich C, Moran NA*

Honeybee gut microbiota promotes host weight gain via bacterial metabolism and hormonal signaling

2017 PNAS 114:4775–4780 DOI  F1000 Recommended

 

  • Meng Y, Li S, Zhang C*, Zheng H*

Strain-level profiling with picodroplet microfluidic cultivation reveals host-specific adaption of honeybee gut symbionts

2022 Microbiome 10:140 DOI

 

  • Sun H, Mu X, Zhang K, Lang H, Su Q, Li X, Zhou X, Zhang X*, Zheng H*

Geographical resistome profiling in the honeybee microbiome reveals resistance gene transfer conferred by mobilizable plasmids

2022 Microbiome 10:69 DOI

 

  • Su Q', Wang Q', Mu X, Chen H, Meng Y, Zhang X, Zheng L, Hu X, Zhai Y*, Zheng H*

Strain-level analysis reveals the vertical microbial transmission during the life cycle of bumblebee

2021 Microbiome 9:216 DOI

 

  • Wu J', Lang H', Mu X, Zhang Z, Su Q, Hu X, Zheng H*

Honey bee genetics shape the strain-level structure of gut microbiota in social transmission

2021 Microbiome 9:225 DOI​​

All Publications

60. Meng Y, Zhang X, Zhai Y, Li Y, Shao Z, Liu S, Zhang C, Xing X, Zheng H*

Identification of the mutual gliding locus as a factor for gut colonization in non-native bee hosts using the ARTP mutagenesis

Microbiome in press

 

59. Zhang Z, Mu X, Cao Q, Zhai Y, Zheng L, Liu Y, Zheng H, Zhang X*

Antibiotic exposure alters the honeybee gut microbiota and may interfere with the honeybee behavioral caste transition

Insect Sci in press

 

58. Yang C, Hu J, Su Q, Zhang Z, Du Y, Wang J, Sun H,... Zheng H, Zhou X*, Zhang X*

Review: A review on recent taxonomic updates of gut bacteria associated with social bees, with a curated genomic reference database

Insect Sci in press DOI

 

57. Liu HMu X, Fan R, Chen J, Ma J, Meng L, Hu X, Zheng H, Liu S, Wang X*

Arecoline causes cognitive impairment and potential addiction via disturbing Kenyon cells in bumblebee brain

Food Sci Hum Wellness in press

 

56. Liu HZheng H, Zhang J, Chen F, Hu X, Wang X*

Review: Review of the toxic effects and health functions of arecoline on multiple organ systems

Food Innov Adv in press

 

55. Zhu L, Wang K, Wu X*, Zheng H, Liao X

Association of specific gut microbiota with polyethylene microplastics caused gut dysbiosis and increased susceptibility to opportunistic pathogens in honeybees

2024 Sci Total Environ 918:170642 DOI 

 

54. Zhang W, Sun C, Lang H, Wang J, Li X, Guo J*, Zhang Z*, Zheng H*

Toll receptor ligand Spätzle 4 responses to the highly pathogenic Enterococcus faecalis from Varroa mites in honeybees

2023 PLoS Pathog 19:e1011897 DOI 

 

53. Lang H, Liu Y, Duan H, Zhang W, Hu X, Zheng H*

Identification of peptides from honeybee gut symbionts as potential antimicrobial agents against Melissococcus plutonius 

2023 Nat Commun 14:7650 DOI

 

52. Li Y, Zhang Y, Luo X, Meng Y, Zhong Z, Zheng H*, Yang Y*

The fecal microbiota from children with Autism impact gut metabolism and learning and memory abilities of honeybees

2023 Front Microbiol 14:1278162 DOI

 

51. Chen J, Mu X, Liu H, Yong Q, Ouyang X, Liu Y, Zheng L, Chen H, Zhai Y, Ma J, Meng L, Liu S*, Zheng H*

Rotenone impairs brain glial energetics and locomotor behavior in bumblebees

2024 Sci Total Environ 907:167870 DOI

 

50. Yu Q', Liu Y', Liu S', Li S, Zhang Q, Zhai Y, Zheng L, Zheng H, Zhai Y*, Wang X*

Lactobacillus melliventris promoted the hive productivity and immune functionality in Bombus terrestris performance in the greenhouse

2023 Insect Sci in press DOI

 

49. Wang X, Zhai Y, Zheng H*

Review: Deciphering the cellular heterogeneity of the insect brain with single-cell RNA sequencing 

2024 Insect Sci 31:314-327 DOI

 

48. Wang X, Cheng X, Liu H, Mu X, Zheng H*

Review: Food nutrition and toxicology targeting on specific organs in the era of single-cell sequencing 

2024 Food Sci Hum Wellness 13:75–89 DOI

Cover Story    (HD)

 

47. Lang H, Wang H, Wang HQ, Zhong Z, Xie X, Zhang W, Guo J, Meng L, Hu X, Zhang X, Zheng H*

Engineered symbiotic bacteria interfering Nosema redox system inhibit microsporidia parasitism in honeybees

2023 Nat Commun 14:2778 DOI 

 

46. Cheng X', Wang C', Liu D', Liao Y, Wang B, Zhang X, Zheng H, Lu Y*

Dynamic artificial cells by swarm nanorobotics and synthetic life chemistry 

2023 Sci China Mater 66:2090–2099 DOI 

 

45. Cheng X', Wang C', Yang J', Liu D, Liao Y, Wang B, Han S, Zhang X, Zheng H*, Lu Y*

Nanotransducer-enabled wireless spatiotemporal tuning of engineered bacteria in bumblebee

2023 Small 19:2370288 DOI

Frontispiece

 

44. Sun H, Li H, Zhang X, Liu Y, Chen H, Zheng L, Zhai Y, Zheng H*

Review: The honeybee gut resistome and its role in antibiotic resistance dissemination 

2023 Integr Zool 18:1014-1026 DOI

 

43. Wang J, Lang H, Zhang W, Zhai Y, Zheng L, Chen H, Liu Y, Zheng H*

Stably transmitted defined microbial community in honeybees preserves Hafnia alvei inhibition by regulating immune system  

2022 Front Microbiol 13:1074153 DOI

 

42. Liu Y, Chen J, Lang H, Zheng H*

Bartonella choladocola sp. nov. and Bartonella apihabitans sp. nov., two novel species isolated from honey bee gut  

2022 Sys Appl Microbiol 45:126372 DOI

 

41. Chang R, Chen J, Zhong Z, Li Y, Wu K, Zheng H*, Yang Y*

Inflammatory bowel disease-associated Escherichia coli strain LF82 in the damage of gut and cognition of honeybees

2022 Front Cell Infect Microbiol 12:983169 DOI

 

40. Meng Y, Li S, Zhang C*, Zheng H*

Strain-level profiling with picodroplet microfluidic cultivation reveals host-specific adaption of honeybee gut symbionts

2022 Microbiome 10:140 DOI

 

39. Yang C, Su Q, Tang M, Luo S, Zheng H, Zhang X*, Zhou X*

Amplicon sequencing of single-copy protein-coding genes reveals accurate diversity for sequence-discrete microbiome populations

2022 Microbiol Spectr 10:e02105-21 DOI

 

38. Zhang Q', Wang Q', Zhai Y, Zheng H*, Wang X*

Impacts of imidacloprid and flupyradifurone insecticides on the gut microbiota of Bombus terrestris

2022 Agriculture 12:389 DOI

 

37. Wang K', Zhu L', Rao L, Zhao L, Wang Y, Wu X*, Zheng H*, Liao X

Nano- and micro-polystyrene plastics disturb gut microbiota and intestinal immune system in honeybee

2022 Sci Total Environ 842:156819 DOI

 

36. Wang X, Qi Y, Zheng H*

Review: Dietary polyphenol, gut microbiota, and health benefits

2022 Antioxidants 11:1212 DOI

 

35.  Zhang Z, Zheng H*

Review: Bumblebees with the socially transmitted microbiome: a novel model organism for gut microbiota research

2022 Insect Sci 29:958-976 DOI

Cover Story


34. Sun H, Mu X, Zhang K, Lang H, Su Q, Li X, Zhou X, Zhang X*, Zheng H*

Geographical resistome profiling in the honeybee microbiome reveals resistance gene transfer conferred by mobilizable plasmids

2022 Microbiome 10:69 DOI

 

33. Zhang Z, Mu X, Cao Q, Shi Y, Hu X, Zheng H*

Honeybee gut Lactobacillus modulates host learning and memory behaviors via regulating tryptophan metabolism

2022 Nat Commun 13:2037 DOI

 

32. Zhang Z, Mu X, Shi Y, Zheng H*

Distinct roles of honeybee gut bacteria on host metabolism and neurological process

2022 Microbiol Spectr 10:e02438-21 DOI

 

31. Li L, Pan H, Pang G, Lang H, Shen Y, Sun T, Zhang Y, Liu J, Chang J, Kang J*, Zheng H*, Wang H*

Precise thermal regulation of engineered bacteria secretion for breast cancer treatment in vivo

2022 ACS Synth Biol 11:1167–1177 DOI

 

30. Zhang W', Zhang X', Su Q, Tang M, Zheng H, Zhou X*

Genomic features underlying the evolutionary transitions of Apibacter to honey bee gut symbionts

2022 Insect Sci 29:259-275 DOI

Cover Story

 

29. Wang X, Zhong Z, Chen X, Hong Z, Lin W, Mu X, Hu X, Zheng H*

High-Fat Diets with Differential Fatty Acids Induce Obesity and Perturb Gut Microbiota in Honey Bee

2021 Int J Mol Sci 22:834 DOI

 

28. Lang H, Duan H, Wang J, Zhang W, Guo J, Zhang X, Hu X, Zheng H*

Specific strains of honeybee gut Lactobacillus stimulate host immune system to protect against pathogenic Hafnia alvei

2021 Microbiol Spectr 10:e01896-21DOI

 

27. Su Q', Wang Q', Mu X, Chen H, Meng Y, Zhang X, Zheng L, Hu X, Zhai Y*, Zheng H*

Strain-level analysis reveals the vertical microbial transmission during the life cycle of bumblebee

2021 Microbiome 9:216 DOI

 

26.  Wu J', Lang H', Mu X, Zhang Z, Su Q, Hu X, Zheng H*

Honey bee genetics shape the strain-level structure of gut microbiota in social transmission

2021 Microbiome 9:225 DOI

 

25. Jieteng Chen, Jieni Wang, Hao Zheng*

Characterization of Bifidobacterium apousia sp. nov., Bifidobacterium choladohabitans sp. nov., and Bifidobacterium polysaccharolyticum sp. nov., three novel species of the genus Bifidobacterium from honey bee gut

2021 Sys Appl Microbiol 44:126247 DOI

 

24. Yulin Song, Vincent Hervé, Renate Radek, Fabienne Pfeiffer, Hao Zheng, Andreas Brune*

Characterization and phylogenomic analysis of Breznakiella homolactica gen. nov. sp. nov. indicate that termite gut treponemes evolved from non-acetogenic spirochetes in cockroaches

2021 Env Microbiol 23:4228–4245 DOI

Cover Story

 

23. Zijing Zhang, Mingfei Huang, Lifei Qiu, Ruihao Song, Zixuan Zhang, Yiwen Ding, Xin Zhou, Xue Zhang*, Hao Zheng*

Diversity and functional analysis of Chinese bumblebee gut microbiota reveal the metabolic niche and antibiotic resistance variation of Gilliamella

2020 Insect Sci 28:302-314 DOI

Cover Story

Most Cited Paper

 

22. Xue Zhang, Daniel E. Deatherage, Hao Zheng, Stratton J. Georgoulis, Jeffery E. Barrick*

Evolution of satellite plasmids can prolong the maintenance of newly acquired accessory genes in bacteria

2019 Nat Commun 10:5809 DOI

Highlighted in Nat Ecol Evol

 

21. Hao Zheng*, Julie Perreau, J. Elijah Powell, Benfeng Han, Zijing Zhang, Waldan K. Kwong, Susannah G. Tringe, Nancy A. Moran*

Division of labor in honey bee gut microbiota for plant polysaccharide digestion

2019 Proc Natl Acad Sci USA 116:25909–25916 DOI

Highlighted in Nat Rev Microbiol: Microbiome

Blog on JGI: Honey Bee Gut Microbiota Divvy Up Dinner

Referenced in Wikipedia

 

20. Xiaofei Wang, Xue Zhang, Zijing Zhang, Haoyu Lang, Hao Zheng*

Review: Honey bee as a model organism to study gut microbiota and diseases

2019 Drug Discovery Today: Disease Models 28:35–42 DOI

 

19. Jieni Wang, Qinzhi Su, Xue Zhang*, Chenyi Li, Shiqi Luo, Xin Zhou, Hao Zheng*

Entomomonas moraniae gen. nov., sp. nov., a member of the family Pseudomonadaceae isolated from Asian honey bee gut, possesses a highly reduced genome

2019 Int J Syst Evol Microbiol Available online DOI

 

18. 张雪, 李兴安, 苏秦之, 曹棋钠, 李晨伊, 牛庆生*, 郑  浩*

综述: 用于蜜蜂和熊蜂肠道微生物分类的细菌16S rRNA数据库优化

2019 生物多样性 27:557–566 DOI

 

17. Zheng H, Steele MI, Leonard SP, Motta EVS, Moran NA*

Review: Honey bees as models for gut microbiota research

2018 Lab Animal 47:317–325 DOI

Cover Story

 

16. 李晨伊, 周欣, 郑浩*

综述: 蜜蜂肠道微生物群落研究进展

2018 微生物学报 58:1016–1024 (Review in Chinese) DOI

 

15. Zheng H*, Powell JE, Steele MI, Dietrich C, Moran NA*

Honeybee gut microbiota promotes host weight gain via bacterial metabolism and hormonal signaling

2017 Proc Natl Acad Sci USA 114:4775–4780 PubMed DOI

F1000 Recommended

 

14. Zheng H, Dietrich C, Brune A*

Genome analysis of Endomicrobium proavitum suggests loss and gain of relevant functions during the evolution of intracellular symbionts

2017 Appl Environ Microbiol 83:e00656-17  PubMed DOI

 

13. Kwong WK*, Zheng H, Moran NA   

Convergent evolution of a modified, acetate-driven TCA cycle in bacteria

2017 Nat Microbiol 2:17067 PubMed DOI

 

12. Mikaelyan A, Thompson CL, Meuser K, Zheng H, Rani P, Plarre R, Brune A*

High-resolution phylogenetic analysis of Endomicrobia reveals multiple acquisitions of endosymbiotic lineages by termite gut flagellates

2017 Environ Microbiol Rep 9:477–483  PubMed DOI

 

11. Zheng H', Dietrich C', Brune A*

Restriction-modification systems as mobile genetic elements in the evolution of an intracellular symbiont

2016 Mol Biol Evol 33:721–725 PubMed DOI

 

10. Zheng H*, Nishida A, Kwong W, Koch H, Engel P, Steele MI, Moran NA

Metabolism of toxic sugars by strains of the bee gut symbiont Gilliamella apicola

2016 mBio 7:e01326-16 PubMed DOI

 

9. Zheng H, Dietrich C, Radek R, Brune A*

Endomicrobium proavitum, the first isolate of Endomicrobia class. nov. (phylum Elusimicrobia) – an ultramicrobacterium with an unusual cell cycle that fixes nitrogen with a Group IV nitrogenase

2016 Environ Microbiol 18:191–204 PubMed DOI

F1000 Recommended

Highlighted Article

Cover Story

 

8. Zheng H, Dietrich C, Thompson CL, Brune A*

Population structure of Endomicrobia in single host cells of termite gut flagellates (Trichonympha spp.)

2015 Microbes Environ 30:92–98 PubMed DOI

Research Paper Award

 

7. Zheng H, Brune A*

Complete genome sequence of Endomicrobium proavitum, a free-living relative of the intracellular symbionts of termite gut flagellates (phylum Elusimicrobia)

2015 Genome Announc 3:e00679-15 PubMed DOI

 

6. Zheng H', Bodington D', Zhang C, Tanji Y, Miyanaga K, Hongoh Y, Xing XH*

Comprehensive phylogenetic diversity of [FeFe]-hydrogenase genes in termite gut microbiota

2013 Microbes Environ 28:491–494 PubMed DOI

 

5. Zheng H, Zhang C, Lu Y, Jiang PX, Xing XH*

Alteration of anaerobic metabolism in Escherichia coli for enhanced hydrogen production by heterologous expression of hydrogenase genes originating from the Synechocystis sp.

2012 Biochem Eng J 60:81–86 DOI

 

4. Liu Z, Lv FX, Zheng H, Zhang C, Wei F, Xing XH*

Enhanced hydrogen production in a UASB reactor by retaining microbial consortium onto carbon nanotubes (CNTs)

2012  Int J Hydrogen Energ 37:10619–10626 DOI

 

3. Feng Q, Wang YX, Wang TM, Zheng H, Chu LB, Zhang C, Chen HZ, Kong XQ, Xing XH*

Effects of packing rates of cubic-shaped polyurethane foam carriers on the microbial community and the removal of organics and nitrogen in moving bed biofilm reactors

2012 Bioresource Technol 117:201–207 PubMed DOI

 

2. Yan ST, Zheng H, Li A, Zhang X, Xing XH*, Chu LB, Ding GJ, Sun XL, Jurcik B

Systematic analysis of biochemical performance and the microbial community of an activated sludge process using ozone-treated sludge for sludge reduction

2009 Bioresour Technol 100:5002–5009 PubMed DOI

 

1. Yan ST, Li A, Zheng H, Luo MF, Xing XH*

Effects of ionic surfactants on bacterial luciferase and α-amylase

2009 Chinese J Chem Eng 17:829–834 DOI

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